Are there any side effects of spironolactone (Aldactone)?

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Some people may have an allergic reaction to spironolactone, causing symptoms such as hives, swelling in the face or throat, or difficulty breathing. If these symptoms occur, get emergency medical attention. Spironolactone may also cause:

  • irregular heartbeat
  • muscle pain or weakness
  • changes in urination
  • drowsiness
  • lightheadedness
  • confusion
  • yellowing of the skin or eyes
  • fever

Talk to your doctor right away if you develop any of those side effects. Other side effects of spironolactone may include:

  • gas
  • nausea
  • stomach pain
  • vomiting
  • dizziness
  • headache
  • skin rash

Talk to your doctor if you're worried about any side effects that develop while taking spironolactone.