Who should not take amiloride and hydrochlorothiazide?

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Amiloride-hydrochlorothiazide (HCTZ) should not be taken by anyone with an allergy to any of its ingredients. Those who have diabetes or kidney disease should not take amiloride-(HCTZ) or, if there are no other alternatives, the dose may need to be modified. People with high blood levels of potassium should have potassium levels closely monitored. In addition, before anyone starts taking amiloride-HCTZ, the doctor needs to know about breathing disorders, lupus, cirrhosis or other liver diseases, gout, a pancreas disorder, heart disease or an allergy to sulfa medications.