What should I know before taking amiloride and hydrochlorothiazide?

You should know that amiloride-hydrochlorothiazide (HCTZ) can increase potassium levels to dangerous amounts in those with severe illnesses, diabetes, kidney problems and elderly people. High potassium levels are potentially fatal and should be monitored carefully. You should not take amiloride-HCTZ if you are taking dofetilide, already have high potassium levels or are taking potassium supplements, salt substitutes that contain potassium or other diuretics that increase potassium levels. You should not take this medication if you have impaired kidney function or difficulty urinating. Prior to taking amiloride-HCTZ, tell your doctor if you have a history of heart, liver or kidney problems, diabetes, gout, asthma or systematic lupus erythematosus. Your doctor should also determine if you are dehydrated or have electrolyte problems, if you have low folic acid levels or if your blood acid levels are elevated. Tell your doctor if you are taking any of the following medications, as they may interact with amiloride-HCTZ: cholestyramine; colestipol; nonsteroidal anti-inflammatory drugs (NSAIDs); barbiturates; cancer chemotherapy drugs; corticosteroids; digoxin; ketanserin; narcotic pain relievers; other medicines for high blood pressure; lithium; and diabetes medicines, including insulin.

Continue Learning about Diuretic

What conditions do diuretics treat?
HCA VirginiaHCA Virginia
The most common conditions diuretics treat are high blood pressure and congestive heart failure. Les...
More Answers
What are the risks of misusing diuretics?
Dr. Mehmet Oz, MDDr. Mehmet Oz, MD
Diuretics should only be taken when prescribed by a doctor to you for a specific reason. Your body n...
More Answers
What is metolazone?
Donna Hill Howes, RNDonna Hill Howes, RN
Metolazone (Zaroxolyn) inhibits sodium reabsorption in a different part of the kidney than loop diur...
More Answers
Do loop diuretics interact with any other medications?
Donna Hill Howes, RNDonna Hill Howes, RN
If you are taking an aminoglycoside, loop diuretics can lead to side effects and should be avoided. ...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.