How soon after starting Microzide will my symptoms improve?

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Microzide (hydrochlorothiazide), a diuretic, or water pill, acts quickly to lower high blood pressure, as well as to reduce fluid retention. It starts to work within two hours and reaches its peak effectiveness in four hours. It will continue working for 24 hours.

High blood pressure, however, does not always have symptoms, so you might not notice that Microzide is working. Do not stop taking Microzide without talking with your doctor first, even if you feel well.