How is organ rejection detected after pancreas transplantation?

The pancreas is more immunologically active and is more likely to suffer rejection than the kidney. Rejection after pancreatic transplantation is also more difficult to detect than after kidney transplantation.

Patients must be diligent about adhering to their medication regimens, as they are important to the long-term success of the transplant operation. Drug regimens are tailored to the needs of each person, but usually patients take several medications to prevent rejection. These have the effect of making patients more susceptible to infection, particularly in the first few months when higher doses are needed.

Rejection is detected by monitoring blood work such as pancreatic enzymes, monitoring blood sugars, and pancreatic biopsies. If tests indicate signs of rejection, patients should be reassured that many people experience episodes of rejection, and such episodes do not indicate that they will lose their new pancreas. Very often, no symptoms are present, and adjusting the immunosuppressant medications resolves the problem.

Continue Learning about Digestive Health

Is Chocolate Good for Your Gut?
Is Chocolate Good for Your Gut?
Mayans concocted a bitter, frothy, hot brew from roasted cocoa bean paste, chili peppers and cornmeal. Later the Aztecs adopted the custom—but sipped ...
Read More
How long can a liver survive outside the body before transplant?
Dr. Ajay K. Sahajpal, MDDr. Ajay K. Sahajpal, MD
In general, ideally a liver will be transplanted under 12 hours. It can survive up to 16 hours, howe...
More Answers
5 Foods for Healthy Digestion
5 Foods for Healthy Digestion5 Foods for Healthy Digestion5 Foods for Healthy Digestion5 Foods for Healthy Digestion
Reach for these when your tummy rumbles.
Start Slideshow
What Should I Look for in a High-Quality Probiotic?
What Should I Look for in a High-Quality Probiotic?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.