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What are symptoms of leaky gut syndrome?

Leopold D. Galland, MD
Internal Medicine
You should suspect Leaky Gut Syndrome if you have:
  • pain in multiple joints
  • a chronic skin condition
  • chronic diarrhea or abdominal pain
  • chronic fatigue
  • chronic depression
  • malaise
  • a feeling of being infected but your doctor can't find the infection
You should also suspect Leaky Gut Syndrome if you use aspirin or anti-inflammatory drugs on a regular basis, or if you're a heavy drinker of alcohol.

Recent research in animals has indicated that Leaky Gut Syndrome may also be associated with difficulty losing or gaining weight, but its association with obesity is still under investigation.
Robynne K. Chutkan, MD
Gastroenterology
In addition to bloating and digestive distress, a lot of the patients I see with leaky gut have a combination of other symptoms like food allergies, chronic sinus infections, achy joints, fatigue, brain fog or unexplained rashes. Typically they’ve been to multiple doctors trying to make sense of their symptoms, and conventional tests and imaging studies have been unrevealing. There can be a feeling of hopelessness and despair, because the symptoms seem so unrelated.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.