What is coenzyme Q10 (CoQ10)?

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Marjorie Nolan Cohn
Nutrition & Dietetics
Coenzyme Q10, also known as CoQ10, is produced by the human body and is necessary for basic functioning in cells. CoQ10 levels are reported to decrease with age and to be low in patients with some chronic diseases such as heart conditions, muscular dystrophies, Parkinson's disease, cancer, diabetes, and HIV/AIDS. Some prescription drugs may also lower CoQ10 levels. CoQ10 helps convert food into energy. CoQ10 is found in almost every cell in the body, and it is a powerful antioxidant.

Antioxidants fight damaging particles in the body known as free radicals, which damage cell membranes, tamper with DNA, and even cause cell death. Scientists believe free radicals contribute to the aging process, as well as a number of health problems, including heart disease and cancer. Antioxidants, such as CoQ10, can neutralize free radicals and may reduce or even help prevent some of the damage they cause.

CoQ10 has been used, recommended, or studied for numerous conditions, but remains controversial as a treatment in many areas.
 
Bryce B. Wylde
Alternative & Complementary Medicine
Coenzyme Q10 (CoQ10) is an important antioxidant in the prevention of heart disease and ameliorates the side effects of heart medication. Some studies have shown that it also slows the progression of early-stage Parkinson’s disease.

CoQ10 plays a critical metabolic role as part of the process by which our cells’ mitochondria convert nutrients into 95% of the energy we need. Although the bodies of younger people are able to manufacture CoQ10, older people may not, making it essential to health.

As a supplement, CoQ10 has recently shown great promise in the treatment or prevention of migraine headaches, heart disease, cancer, neurodegenerative diseases, and many other conditions.
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Dr. Doris Day, MD
Dermatology
Coenzyme Q10 (CoQ10) is another very important ingredient that is getting a lot of attention lately both in skin care products and as a supplement. It is also called ubiquinone since it is found in such a wide variety of foods and because it is produced by every cell in the body. This makes it ubiquitous, hence the name ubiquinone. It is fat soluble and it is an antioxidant and a significant coenzyme in several critical pathways of energy production of the body. The ability of the body to produce CoQ10 decreases over time and in those on certain types of medicine such as certain cholesterol-lowering drugs. It is found in small amounts in almost every food you eat.
Jacob Teitelbaum
Integrative Medicine
Coenzyme Q10 is a naturally occurring substance created by your body to facilitate energy production in your cells. Some people's bodies do not produce enough Coenzyme Q10 for cells to function properly, so adding this substance as a supplement may help treat muscle-wasting diseases, such as mitochondrial disorders, Parkinson's disease, amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), Huntington's disease (HD) and muscular dystrophy (MD).

Doctors may also prescribe Coenzyme Q10 to treat heart disease, cancer, AIDS and gum disease. This drug's cancer-fighting ability may be due to the fact that it is an antioxidant, a substance that thwarts cell-damaging free radicals.
Although the Food and Drug Administration has given provisional approval to prescribe Coenzyme Q10 for diseases that have few other successful treatment options, studies have not yet determined this drug's effectiveness at treating or preventing any disease. Coenzyme Q10 is also known as Co Q10, mitoquinone, Q10, ubidecarenone, ubiquinone and vitamin Q.
 
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Dr. Mehmet Oz, MD
Cardiology (Cardiovascular Disease)
Coenzyme   Q10 has gained a lot of attention in recent years because of its alleged ability to prevent cardiovascular aging-as well as for helping critically ill patients awaiting heart transplants. I believe that it does help your heart   and that it may also help prevent your brain from aging.

Found naturally in the body's organs, coenzyme Q10 helps stimulate energy pathways at a cellular level, notably in muscle tissue and in all brain and nervous tissue cells. Our bodies naturally produce Q10-but only when we're not lacking in other nutrients, especially vitamin B6. In studies of hypertension, coenzyme Q10 seemed to lower high blood pressure; however, one study of patients with metabolic syndrome showed no improvement in blood pressure. Another study showed benefits for glycemic control for those with type 2 diabetes.

Studies have also been done with patients suffering from migraines, Lou Gehrig's disease, Parkinson's disease, and other conditions, but results have been inconclusive or mixed.
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d minerals to fiber and herbal remedies, these supplements are not regulated in the same way as either food or medicine. Some of them are backed by solid research, others are folk remedies or proprietary cures. If your diet does not include enough of certain vitamins or minerals, a supplement may be a good idea. Natural treatment for conditions like constipation may be effective. But because these substances are unregulated, it is always a good idea to educate yourself about the products and to use common sense when taking them. This is even more true if you are pregnant or taking a medicine that may be affected by supplements.
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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.