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What is creatinine?

The chemical molecule creatinine is present in the liquid portion (serum) of the blood. It is produced by creatine, another molecule, which is a component of muscle.

Jeanne Morrison, PhD
Family Medicine
Creatinine is a waste product in your blood that comes from muscle activity.  Creatinine is normally removed from your body by your kidneys.  When your kidneys are not functioning like they should, creatinine builds up in the blood.  If you have an elevated creatinine level, close monitoring by your doctor is necessary.
Creatinine is a waste product from protein in the diet and from the muscles of the body. Creatinine is removed from the body by the kidneys. As kidney disease progresses, the level of creatinine in the blood increases.
Creatinine is a chemical excreted by the kidneys. When the kidneys are working less well, creatinine levels increase. The higher the creatinine number the less efficient the kidney works. Normal values are around 1.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.