Who should not receive gadoversetamide injection?

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Gadoversetamide injection should not be administered to people with renal insufficiency (limited kidney function), including renal insufficiency during hospitalization for liver transplant or renal insufficiency associated with hepatorenal syndrome (a serious disorder of liver and kidneys at the same time). Even if you do not have any known kidney disorders, your doctor should screen you for them before administering gadoversetamide injection. You should also avoid this agent if you have a history of allergies to it. People with certain past or current conditions should not take gadoversetamide except on the recommendation of their doctor. They include:

  • kidney disease
  • heart disease
  • seizures
  • respiratory allergies
  • asthma
  • anemia or hemoglobinopathies (like sickle cell anemia or hemolytic anemia)

Children under two years of age should not be administered gadoversetamide injection because studies have not been conducted with this subgroup. The FDA classifies gadoversetamide as a Pregnancy Category C drug, meaning that it may pose harm to a fetus. If you are pregnant or planning to become pregnant, discuss with your doctor whether the risks of receiving gadoversetamide injection outweigh the possible benefits. If you are breastfeeding, stop for 72 hours after the injection. Do not keep any milk you express or pump during this time period.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.