What should I expect during a cosyntropin (Cortrosyn) stimulation test?

You can expect the following during a cosyntropin (Cortrosyn) stimulation test:
  • You will be lying down. A nurse and a technician will do the test.
  • Your blood pressure, temperature, and pulse will be checked.
  • The technician will draw a sample of blood from your arm.
  • The nurse will insert an intravenous catheter (IV) into your arm or hand. This IV will then be flushed with a small amount of saline.
  • A medicine called cosyntropin will be injected into the IV. This will take about one minute. During this injection, you may feel warm or flushed, or have a "butterfly" feeling in your stomach. Some people have an empty stomach feeling or slight nausea. These feelings go away in one to two minutes.
  • After the medicine is injected, the nurse will inject a small amount of saline again.
  • At 30 and 60 minutes after the injection of cosyntropin, the technician will draw a blood sample from your arm.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.