Why are antidepressants prescribed for diabetic peripheral neuropathy?

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Treatment for diabetic peripheral neuropathy includes managing nerve pain. Antidepressants may be prescribed to treat your nerve pain even if you do not have depression. They help relieve pain by interfering with the parts of the nervous system that cause pain. Tricyclic antidepressants may cause unpleasant side effects, but newer antidepressants called serotonin and norepinephrine reuptake inhibitors may have fewer side effects. You and your doctor will need to decide if you should treat diabetic peripheral neuropathy with an antidepressant.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.