What should I know before taking a GLP-1 receptor agonist?

Dr. Darria Long Gillespie, MD
Emergency Medicine
If you have had thyroid cancer or a family history of thyroid cancer, you should not take a GLP-1 receptor agonist.

If you have gastropathy, GLP-1 agonists can lead to side effects and should be avoided.

If you have had pancreatitis, GLP-1 receptor agonists may not be good options for you.

If you have impaired kidney function, GLP-1 agonists may not be good options for you. Exenatide should not be taken by people with severe kidney impairment or end-stage renal disease.

If you have impaired liver function, dulaglutide may not be a good option for you.

If you have multiple endocrine neoplasia syndrome type 2 (MEN-2), you should not take a GLP-1 receptor agonist.

You should not take Saxenda if you are pregnant, planning to become pregnant, or may be pregnant. It is not known if other GLP-1 receptor agonists are safe for pregnant women.

You should not take a GLP-1 receptor agonist if you are breastfeeding.

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