What is Tresiba?

Tresiba (insulin degludec) is a type of insulin that has been sold in Europe since 2013. Tresiba is available in U-100 and U-200 forms.

In clinical trials, the drug was linked to decreased low blood sugar (hypoglycemia), especially at night. In most studies, weight gain was similar when comparing Tresiba with another type of insulin called Lantus.

Tresiba allows a flexible dosing schedule and lasts more than 24 hours. With the medicine's FlexTouch pen, one can receive a dose of up to 160 units at a time. (It is not uncommon for some users with type 2 diabetes to use that much). This means you don’t have to take your dose at the same time every day. For example, you could take your dose Sunday morning at 7:00 a.m., and then again at 11:00 a.m. on Monday.
Tresiba is insulin degludec, a very long-lasting form of injectable insulin, prescribed for the treatment of both type 1 and type 2 diabetes. It is supplied as a clear liquid in either 100 units/mL or 200 units/mL doses, for once-daily injection to achieve glycemic control. It is injected with the FlexTouch pen. Side effects may include itching, rash, edema, weight gain, changes in body fat, or allergic reactions, among others. Hypoglycemia or low potassium levels may occur -- symptoms to watch for include shaking, seizures, sweating, vision problems, hunger, headache, agitation, weakness or tiredness, abnormal heart rhythm, spasms, or constipation. Tresiba has not been approved for use in children. Follow directions for self-administration carefully. 

Continue Learning about Diabetes


Diabetes mellitus (MEL-ih-tus), often referred to as diabetes, is characterized by high blood glucose (sugar) levels that result from the body’s inability to produce enough insulin and/or effectively utilize the insulin. Diabetes ...

is a serious, life-long condition and the sixth leading cause of death in the United States. Diabetes is a disorder of metabolism (the body's way of digesting food and converting it into energy). There are three forms of diabetes. Type 1 diabetes is an autoimmune disease that accounts for five- to 10-percent of all diagnosed cases of diabetes. Type 2 diabetes may account for 90- to 95-percent of all diagnosed cases. The third type of diabetes occurs in pregnancy and is referred to as gestational diabetes. Left untreated, gestational diabetes can cause health issues for pregnant women and their babies. People with diabetes can take preventive steps to control this disease and decrease the risk of further complications.

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.