What is maturity-onset diabetes of the young (MODY)?

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Maturity-onset diabetes of the young (MODY) usually affects young adults, but can also affect teens and children. It can be misdiagnosed as type 1 in younger patients. Adults with MODY develop diabetes at a younger age than most type 2 patients and do not tend to be overweight or sedentary. In the past, people with MODY were often told they had a form of type 2 diabetes. We now know that MODY is caused by a genetic mutation that leads to impaired insulin secretion. Insulin resistance, which is often found in type 2 diabetes, does not usually occur in MODY. If you have MODY, you may be able to manage your blood glucose levels through diet and exercise alone, at least for a while. However, therapies that work for people with type 2 diabetes do not always work for people with MODY. You may have more success with insulin therapy or oral agents that stimulate insulin secretion.

Continue Learning about Diabetes

Diabetes

Diabetes mellitus (MEL-ih-tus), often referred to as diabetes, is characterized by high blood glucose (sugar) levels that result from the body’s inability to produce enough insulin and/or effectively utilize the insulin. Diabetes ...

is a serious, life-long condition and the sixth leading cause of death in the United States. Diabetes is a disorder of metabolism (the body's way of digesting food and converting it into energy). There are three forms of diabetes. Type 1 diabetes is an autoimmune disease that accounts for five- to 10-percent of all diagnosed cases of diabetes. Type 2 diabetes may account for 90- to 95-percent of all diagnosed cases. The third type of diabetes occurs in pregnancy and is referred to as gestational diabetes. Left untreated, gestational diabetes can cause health issues for pregnant women and their babies. People with diabetes can take preventive steps to control this disease and decrease the risk of further complications.
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