What is duodenal-jejunal bypass surgery for type 2 diabetes?

Duodenal-jejunal bypass (DJB) is an investigational procedure, developed by Dr. Rubino of NewYork-Presbyterian Hospital, which has been used in clinical research studies for patients with type 2 diabetes who are not obese. The procedure can be performed in two technical variants (see Technique below) and has been reported to result in good control of diabetes in the short term. Long-term results are being evaluated through research studies.

The operation consists of a stomach-preserving bypass of a short segment of proximal small intestine, equivalent to the amount of intestine bypassed in a standard Roux-en-Y gastric bypass. DJB may be associated with a sleeve resection of the stomach to reduce potential for marginal ulcerations and increase the weight loss effect if performed in mildly or severely obese patients. Long-term data about the efficacy of this procedure are not yet available.

Continue Learning about Diabetes


Diabetes mellitus (MEL-ih-tus), often referred to as diabetes, is characterized by high blood glucose (sugar) levels that result from the body’s inability to produce enough insulin and/or effectively utilize the insulin. Diabetes ...

is a serious, life-long condition and the sixth leading cause of death in the United States. Diabetes is a disorder of metabolism (the body's way of digesting food and converting it into energy). There are three forms of diabetes. Type 1 diabetes is an autoimmune disease that accounts for five- to 10-percent of all diagnosed cases of diabetes. Type 2 diabetes may account for 90- to 95-percent of all diagnosed cases. The third type of diabetes occurs in pregnancy and is referred to as gestational diabetes. Left untreated, gestational diabetes can cause health issues for pregnant women and their babies. People with diabetes can take preventive steps to control this disease and decrease the risk of further complications.

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