Which other drugs can interact with Neosporin ophthalmic ointment?

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Neosporin ophthalmic ointment (neomycin, polymyxin and bacitracin) can be used safely in combination with most other medications. However, it is still a good idea to tell your doctor about all of the medications you are taking (prescription and over-the-counter), as well as all vitamins and nutritional or herbal supplements. Be sure to tell your doctor if you are using other eye medications.