How many times can I repeat the malathion treatment to get rid of lice?

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If you find live lice seven to nine days after your first treatment with malathion (Ovide) lotion, you should repeat the treatment. However, if the lotion does not seem to be killing head lice and their eggs (nits) after two treatments, don't use it again. Ask your doctor or pharmacist if you should switch to a different lice-killing product.