What are types of injectable wrinkle fillers?

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Botox is the best known injectable wrinkle filler, but there are several others that are also approved by the FDA:
  • Botox injections. Botulinum (or botulism) toxin type A (Botox Cosmetics, Dysport) is a prescription drug that may be used to temporarily improve the appearance of moderate to severe frown lines between the eyebrows. It is a protein produced by the bacterium clostridium botulinum. When used as an anti-aging agent, small doses of a purified, sterile form of the toxin are injected into certain facial muscles to temporarily paralyze and weaken them. When the muscles can't contract normally, frown lines disappear. According to the FDA, Botox treatments should not be injected more frequently than once every three months, and the lowest effective dose should be used. The most common side effects include headache, dry eyes and mouth, flu-like symptoms, nausea and weakness of the muscles near the injection site. Check with your doctor if any of these side effects persist. Less frequent adverse reactions include fever, bleeding at the injection site, irregular heartbeat and vision changes. If you experience any of these, seek medical attention right away. These reactions are often temporary but could several months.
  • Restylane and Perlane are soft-tissue fillers used for moderate to severe wrinkles around the nose and mouth. They use a synthetic form of hyaluronic acid. Hyaluronic acid is a sugar found in human skin that forms part of the matrix holding skin cells together. It is also a component in collagen. These products attract water like a sponge, filling and plumping the tissue. Perlane contains more hyaluronic acid and therefore works better for filling deep lines, while Restylane is used in fine lines or in thin-skinned people. One injection is needed for 6 to 12 months of effectiveness, depending on the patient and the area being treated.
  • Hylaform is used for moderate to severe wrinkles and folds. It is a form of hyaluronic acid made from rooster combs.  
  • Juvederm, also a soft-tissue filler for moderate to severe wrinkles, is a natural hyaluronic acid, which works similarly to Restylane, but degrades more slowly and lasts longer. The treatment may last 12 months.
  • Captique is used for wrinkles around the nose and mouth. Results are immediate. Two to three touchups a year are usually needed to maintain results.
Juvederm, Restylane and Perlane now come with lidocaine in the product, which makes the procedure much more comfortable.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.