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How can DHEA affect depression?

Some studies suggest the molecule dehydroepiandrosterone (DHEA) may be an effective treatment for major depression when used alone or as an adjunct to antidepressants. DHEA may work by increasing serotonin levels in the brain and blocking the effects of certain stress hormones, such as cortisol. Potential adverse effects associated with use of DHEA include oily skin, acne, deepening of the voice, overactivation, disinhibition, aggression, mania or psychosis. The verifiable benefits of DHEA in depression is currently under investigation.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.