What are the symptoms of Cushing's syndrome?

Signs and symptoms of Cushing's syndrome include:
  • Weight gain, particularly around the gut or mid-section.
  • Moon face, a rounded shape of the face that develops from a specific pattern of fat distribution.
  • Easy bruising when the arms and legs are frequently covered with multiple bruises.
  • Buffalo hump, a mound of fat at the base of the back of the neck
  • Abnormal hair growth as women with Cushing's syndrome may develop more hair growth on the face or near the belly button.
  • Edema (leg swelling) due to excess fluid buildup in the lower legs and feet.
  • Stretch marks (purple striae), most common around the sides and lower abdomen, these may have a pink, red, or purple color.
  • Hypertension (high blood pressure)
  • Diabetes (high blood sugar levels)
  • Mood changes as many patients feel hyper, others may experience sudden emotional ups and downs or be quick to anger.
  • Thinning of the skin when the skin may develop a shiny, paper-thin quality and may rip or tear easily.
  • Ruddy complexion (plethora), a reddening of the face or cheeks.
  • Muscle weakness when the arms and legs may become skinny like twigs from muscle wasting.
  • Menstrual disturbances when a woman's period may be irregular or stop altogether.
Susie Whitworth
The symptoms of Cushing's syndrome are a round face, obesity of the upper body, slender arms and legs and fat around the neck area. The skin heals slowly and bruises easily. The bones become weak and fracture easily. Other symptoms that my be present include: high blood pressure, high blood sugar, a fatty hump between the shoulders, weak muscles, fatigue, increased thirst, increased urination, depression or anxiety.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.