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What medications do inhaled short-acting beta-agonists interact with?

Donna Hill Howes, RN
Family Practitioner

If you are taking a beta blocker, a strong CYP3A4 inhibitor, a drug that prolongs the QTc interval, or a tricyclic antidepressant, short-acting inhaled beta-agonists can lead to serious side effects and should be avoided.

If you are taking or have taken an MAO inhibitor within the past 2 weeks, short-acting beta-agonists can lead to serious side effects and should be avoided.

If you are taking bromocriptine, digoxin, or theophylline, a short-acting beta-agonist may not be a good option for you.

If you are taking a long-acting bronchodilator, taking a short-acting beta agonist in high doses on an as-needed basis has not been shown to be of added benefit and is not recommended.

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.