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What conditions can be helped by medroxyprogesterone injections?

Donna Hill Howes, RN
Family Practitioner

Medroxyprogesterone shots do not contain estrogen. They may be a good choice for women who want to use a hormonal form of birth control, but have had side effects with estrogen in the past.

Medroxyprogesterone can reduce the pain of endometriosis. It is approved for treating this condition and is as effective as leuprolide.

Medroxyprogesterone can reduce the frequency and intensity of sickle cell crises.

Most women who use medroxyprogesterone have very light or missed periods. After one year of use, up to 50% of women stop having periods. After 5 years of use, 80% of women no longer have monthly periods.

Medroxyprogesterone can reduce PMS symptoms, including cramps, pain, mood changes, headaches, breast tenderness, and nausea. And it can help limit pain and other symptoms during your period. 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor. 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.