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How does major depression affect me?

Diana Meeks
Diana Meeks on behalf of Sigma Nursing
Family Practitioner

Neurotransmitters, such as serotonin, are chemicals that send information to the brain and are responsible for mood. If the brain does not receive the information correctly from the neurotransmitters, the result may be major depression. Because neurotransmitters help control mood, these changes can cause you to feel sad for an extended time. Many of the medical treatments available for clinical depression regulate the levels of neurotransmitters in the brain in order to stabilize mood.

If you have major depression, you may experience many changes in mood. The things you used to enjoy may not be enjoyable anymore, and there’s a general loss of interest in life. Depression can cause sleep problems, making it hard to fall and stay asleep. If you don't get enough ZZZs, you'll think unclearly and feel sluggish the next day. Major depression causes lost productivity at work. If you arrive late or take too long on tasks, coworkers may notice. Resentments may form, affecting work relationships, and you could be pegged as lazy or disorganized.

When major depression sets in, your spouse or partner may wonder what he or she did wrong. Loss of sex drive can be frustrating for your spouse, adding fuel to the idea that you aren't attracted to or don't care about them anymore. Your partner may even blame his or herself for your behavior. Relationship problems only lead to more depression, and it becomes a vicious cycle.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.