What causes large-artery atherothrombotic stroke?

Large-artery atherothrombotic stroke occurs when atherosclerotic plaque builds up and narrows an artery in any of four strategic locations -- the origin of the internal carotid artery, the siphon portion of the internal carotid artery, the middle cerebral artery stem, or the junction of the distal vertebral arteries and the basilar artery. If the plaque ruptures, a clot may grow to obstruct an artery in the brain or break off and travel to another artery, causing an artery-to-artery stroke. Damage from artery-to-artery strokes can grow worse when atherosclerosis triggers a second stroke; when brain swelling increases pressure inside the skull; or when bleeding occurs, causing a hemorrhagic stroke known as a conversion. This type of stroke accounts for about 15% of all ischemic strokes.

Continue Learning about Causes Of Ischemic Stroke

What increases my risk for an ischemic stroke?
Honor Society of Nursing (STTI)Honor Society of Nursing (STTI)
People with family members that have had a stroke are at a greater risk for having a stroke themselv...
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Does ischemic stroke run in families?
Honor Society of Nursing (STTI)Honor Society of Nursing (STTI)
A history of either parent having had an ischemic stroke raises the risk that their children will ha...
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How does atherosclerosis cause an ischemic stroke?
Benjamin T. Cohen, MDBenjamin T. Cohen, MD
Atherosclerosis of the arteries of the neck and brain can cause a stroke. In this video, Ben Cohen, ...
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What is an embolic stroke?
Univ. of Nev. School of Medicine, Family MedicineUniv. of Nev. School of Medicine, Family Medicine
An embolic stroke is a stroke caused by either a traveling blood clot or a piece of plaque (fatty de...
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