Talk to your doctor before taking midodrine hydrochloride if you have other heart or blood vessel problems besides low blood pressure, including high blood pressure. Tell your doctor about any kidney problems or problems you may have urinating. If you have an overactive thyroid or pheochromocytoma, talk to your doctor before taking midodrine hydrochloride. If you have vision disturbances, glaucoma, diabetes, or liver problems, talk to your doctor before taking midodrine hydrochloride.
Midodrine hydrochloride may not be safe for use during pregnancy and breast-feeding. Midodrine hydrochloride can cause increases in blood pressure when you lie down. You should take midodrine hydrochloride three to four hours before bedtime and avoid lying down for prolonged periods during the day.
Midrodrine hydrochloride can cause dizziness when standing from a seated or reclining position. Drinking alcohol with midodrine hydrochloride can make this side effect worse. You should avoid driving or operating tools or machinery until you know how midodrine hydrochloride will affect you. If you must have surgery, no matter how minor, while taking midodrine hydrochloride, tell the surgeon or dentist that you are taking midodrine hydrochloride.