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What should I know before taking BiDil (hydralazine and isosorbide)?

Donna Hill Howes, RN
Family Practitioner

If you have severe anemia, or systolic blood pressure below 90 mm Hg, you should not take a nitrate.

If you have coronary artery disease, a stroke or transient ischemic attack (TIA), or severe kidney impairment, hydralazine may not be a good option for you.

If you have angle-closure or open-angle glaucoma, a nitrate may not be a good option for you.

If you have mitral valve rheumatic heart disease, you should not take hydralazine.

If you are pregnant, planning to become pregnant, or may be pregnant, hydralazine may not be a good option for you. It is not known if it is safe for pregnant women.

If you are breastfeeding, hydralazine and isosorbide dinitrate may not be good options for you. It is not known if these drugs can be passed into breast milk.

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.