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What should I know about bupropion hydrochloride extended-release?

Before taking bupropion hydrochloride extended-release you should know that, as with many antidepressants, bupropion hydrochloride extended-release can cause thoughts of suicide in the first days of treatment. This effect is more common in people younger than 24 years old, but has been reported in adults as well. Your doctor will want to see you regularly until you have been on bupropion hydrochloride extended-release for at least 12 weeks.

Additionally, you may not be able to take this drug if you have taken an MAOI (monoamine oxidase inhibitor) drug (such as isocarboxazid) in the last 14 days, are taking another form of bupropion (such as Zyban), have epilepsy or another seizure disorder, have been diagnosed with an eating disorder such as anorexia or bulimia or have bipolar disorder. If you have recently stopped using alcohol or sedatives (such as Valium), are pregnant, breast-feeding, or have problems with your heart, blood pressure, brain (such as a history of head injury), kidneys, or liver you may not be able to take this drug.

Smoking cigarettes may make the side effects of bupropion hydrochloride extended-release worse, and alcohol may increase your risk of having a seizure. Talk to your doctor about all medications you are taking before starting on this drug, and about any risks that may be particular to your condition.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.