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Who should not take bupropion hydrochloride sustained-release?

You should not take bupropion hydrochloride sustained-release if you are less than 18 years old, as it has been shown to cause an increase in suicidal thoughts in children and adolescents.

People who have epilepsy or another seizure disorder should not take bupropion hydrochloride sustained-release, as it can worsen seizures. Bupropion hydrochloride sustained-release can also make other mental illnesses worse, so you should not take it if you have been diagnosed with mental illnesses such as anorexia, bulimia, or bipolar disorder.

Women who are pregnant or breast-feeding should not take bupropion hydrochloride sustained-release because it is currently unknown whether the drug will harm the developing fetus or the newborn baby.

You should also not take bupropion hydrochloride sustained-release if you have problems with your heart, blood pressure, brain (such as a history of head injury), kidneys, or liver. There are a number of medications that should not be mixed with bupropion hydrochloride sustained-release.

If you have recently reduced your alcohol or sedative intake drastically or if you often drink alcohol, you should not take bupropion hydrochloride sustained-release. People who have taken an MAOI (monoamine oxidase inhibitor) drug (such isocarboxazid) in the last 14 days should also not take bupropion hydrochloride sustained-release. You should also not take this drug if you are taking another form of bupropion, such as Zyban.

Speak with your doctor if you have any concerns about whether bupropion hydrochloride sustained-release is the appropriate treatment for your depression.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.