Can calcifications in the breast turn into cancer?

Lisa A. Tolnitch, MD
Calcifications on mammography do not themselves turn into cancer. They can be a marker especially in certain patterns of an evolving cancer. Worrisome features are pleomorphic calcifications (different sizes and shapes in a group), branching forms (following the branches of a milk duct), or casting calcifications. Those features usually require a biopsy under mammogram guidance with a core needle. 

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