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What are the different types of von Willebrand disease (VWD)?

There are three types of von Willebrand disease (VWD):

  •  Type 1, in which people have unusually low levels of von Willebrand factor (VWF), is the most common and least serious form of the disease. People with type 1 VWD may also have low levels of another kind of blood-clotting protein called factor VIII.
  • In type 2, the body makes the right amount of VWF but the protein doesn't work properly. Type 2 is divided into four subtypes, depending on the specific problem with the VWF. It is important to know which subtype people have, because each may require different treatment.
  • People with type 3 VWD have little or no VWF and low levels of factor VIII. This is considered the most severe form of the disease.

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