Blood Diseases

What is sickle beta-plus thalassemia?

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  • Sickle beta-plus thalassemia is a form of sickle cell disease. It describes the condition resulting from a hybrid of two genetic defects in the gene for making hemoglobin - an essential component of red blood cells. It occurs in the presence of one allele for sickling (deformed) hemoglobin, and one allele for moderate beta thalassemia. Sickle beta-plus thalassemia closely resembles a mild case of a sickle cell anemia. It is a lifelong condition, but not necessarily debilitating.

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