Advertisement

What is trigonitis?

Despite its name indicative of inflammation, trigonitis is a metaplastic process. The exact primary cause is not known, however, squamous metaplasia in the bladder usually occurs in response to an irritative (prolonged indwelling catheter placement) or infectious process. The occurrence of trigonitis varies according to many reports. Non-keratinizing squamous metaplasia of the bladder neck and trigone can be seen in 50-70% of premenopausal women and is considered a normal variant. Trigonitis, or non-keratinizing squamous metaplasia, is considered nonthreatening and without malignant prospective.

Nevertheless, it must be distinguished from keratinizing squamous metaplasia, also known as leukoplakia. Leukoplakia is thought to be a reaction of the normal urothelium to harmful stimuli and is commonly considered a premalignant lesion that may develop to squamous cell carcinoma in 20% of patients. Squamous metaplasia of the trigone is nearly absent in children and it appears virtually exclusively in women of reproductive age.

 

 

 

Continue Learning about Bladder Disease

Worst Case Scenario: I'm Holding It In
Worst Case Scenario: I'm Holding It In
Can holding your urine cause damage? Find out in this video from Dr. Oz. Medically reviewed in May 2018.
Read More
What causes your bladder to drop?
Arthur R. Crowley, MDArthur R. Crowley, MD
A dropped bladder, also called prolapsed bladder or cystocele, is a medical condition that affects t...
More Answers
What is vesicoureteral reflux?
Sangtae Park, MDSangtae Park, MD
This is an abnormal, congenital condition where the urine from the bladder enters the kidney backwar...
More Answers
What Are the Symptoms of Interstitial Cystitis/Painful Bladder Syndrome?
What Are the Symptoms of Interstitial Cystitis/Painful Bladder Syndrome?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.