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How can endometrial biopsies predict the chances of successful pregnancy?

After ovulation the lining to the womb or endometrium, prepares for implantation of the fertilized egg or embryo. Once the embryo reaches a certain size, it is ready to attach to the uterine lining. The endometrial biopsy is a method to evaluate the development of the endometrium or histology. An endometrial biopsy can also be used to help fertility specialists evaluate markers of uterine receptivity. Certain proteins are required for successful pregnancy to occur and might be missing in certain conditions, such as endometriosis, tubal disease or in polycystic ovary syndrome (PCOS). The biopsy requires proper timing and should be performed 8 or 9 days after the luteinizing hormone (LH) surge has occurred.
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