What are IL-5 antagonists?

Donna Hill Howes, RN
Family Practitioner

IL-5 (interleukin-5) antagonists are drugs that limit the production of eosinophils in the body. Eosinophils are white blood cells that trigger inflammation and asthma symptoms. IL-5 antagonists include mepolizumab (Nucala) and reslizumab (Cinqair). Mepolizumab is given once every 4 weeks by injection. Reslizumab is given once every 4 weeks by intravenous infusion.

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