What side effects do Truvada and raltegravir have?

Donna Hill Howes, RN
Family Practitioner

Side effects may include anxiety, depression, fatigue, dizziness, headaches, insomnia, inflammation of the sinuses or throat, abnormal skin sensations, muscle or joint pain, cough, fever, abdominal pain, indigestion, nausea, vomiting, diarrhea, and rash. Body fat may accumulate on the upper back and abdomen, with a reduction in the face, arms, and legs.

More serious side effects include a buildup of lactic acid in the blood, an enlarged liver, severe skin reactions, and weakened bones with pain and fractures. Your immune system may begin to attack healthy cells, causing diseases such as Graves disease and Guillain-Barre syndrome. Some people have an allergic reaction to the drugs. 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor.

Continue Learning about Antiviral

Is famciclovir safe for pregnant or breast-feeding women?
Stacy Wiegman, PharmDStacy Wiegman, PharmD
We don’t know if famciclovir is safe for women who are pregnant or breastfeeding.  The animal studie...
More Answers
What should I know before taking Triumeq (or Epzicom and dolutegravir)?
Dr. Darria Long Gillespie, MDDr. Darria Long Gillespie, MD
Your doctor will need to measure your liver enzymes and kidney function before starting treatment. Y...
More Answers
What side effects do Technivie and ribavirin have?
Donna Hill Howes, RNDonna Hill Howes, RN
Side effects may include fatigue, general weakness, headache, anxiety, flu-like symptoms, insomnia, ...
More Answers
What is Viekira Pak?
Donna Hill Howes, RNDonna Hill Howes, RN
Viekira is a combination of 4 drugs in 3 pills. These are ombitasvir, paritaprevir, ritonavir, and d...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.