What side effects do Truvada and dolutegravir have?

Donna Hill Howes, RN
Family Practitioner

Side effects may include anxiety, depression, dizziness, headaches, insomnia, inflammation of the sinuses or throat, abnormal skin sensations, muscle or joint pain, cough, fever, abdominal pain, indigestion, nausea, vomiting, diarrhea, gallstones, and a rash. Body fat may accumulate on the upper back and abdomen, with a reduction in the face, arms, and legs.

More serious side effects include a buildup of lactic acid in the blood, an enlarged liver, and weakened bones with pain and fractures. Your immune system may begin to attack healthy cells, causing diseases such as Graves disease and Guillain-Barre syndrome. 

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