What are ergothioneine supplements?

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  • Ergothioneine is a naturally occurring, water-soluble amino acid of plant origin that accumulates in animal tissues. Dietary sources of ergothioneine include various types of mushrooms (king bolete, oyster mushroom), chicken liver, pork liver, pork kidney, oat bran, and beans (black turtle bean, red kidney bean).

    Ergothioneine is a water-soluble thiol compound that is of interest to scientists and consumers for its potential beneficial effects as an antioxidant, which may protect against oxidative stress, as well as its anti-inflammatory, neuroprotective, and antiaging properties. Due to its potential benefits for the skin, it is found in some skin care products.

    Ergothioneine cannot cross the plasma membrane of cells unless they express the ergothioneine transporter ETT (originally designated as OCTN1; human gene symbol SLC22A4). Ergothioneine specifically accumulates to millimolar concentrations in cell types that are normally subjected to high levels of oxidative stress (including erythrocytes and plasma). In humans, abnormal ETT and ergothioneine levels have been implicated in rheumatoid arthritis and Crohn's disease.

    You should read product labels, and discuss all therapies with a qualified healthcare provider. Natural Standard information does not constitute medical advice, diagnosis, or treatment.

    For more information visit https://naturalmedicines.therapeuticresearch.com/
This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.
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