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Can we make drugs based on CART to reduce appetite?

Dr. Mehmet Oz, MD
Cardiology (Cardiovascular Disease)
Cocaine and amphetamines stimulate a chemical in the brain that increases metabolism and reduces appetite—called CART, which is an abbreviation for cocaine amphetamine regulatory transcript). This is one reason why cocaine addicts don't gain weight.

It's unclear whether CART will be the basis for effective weight-loss treatments, but researchers are studying the neurological effects these drugs have on appetites to see if they could lead to long-term pharmaceutical solutions to weight-loss (without, of course, the dangerous side effects of illicit drugs).
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