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Can ifosfamide affect urinary health?

Ifosfamide (Ifex), a drug that treats testicular and other types of cancer, may cause serious urinary health problems. These include:
  • hemorrhagic cystitis (bladder inflammation with bleeding)
  • painful urination
  • urinary frequency (urgent urination)
  • bladder irritation
  • renal toxicity (poisoning of the kidneys)
To keep your kidneys working properly while you're receiving ifosfamide, you should drink or receive intravenously around ten 8-ounce glasses of fluid daily and urinate frequently. Your doctor may also prescribe a medication called mesna, which helps prevent urinary side effects. This liquid is mixed with juice and taken by mouth, or is injected into a vein.


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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.