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What should I know about temsirolimus before taking it?

Temsirolimus can harm a fetus and should not be taken by pregnant women. Men who are taking this medication should not contribute to a pregnancy because it can cause birth defects. It is not known if this drug is passed in breast milk, but women should not breast-feed while taking this medication. Temsirolimus can lower blood cells and you may bleed easily if injured. It weakens your immune system and causes you to be more susceptible to infection. You should avoid contact with people who are sick with colds or viruses. Temsirolimus can cause dangerous lung inflammation, so tell your doctor if you have any new or worsening breathing problems while taking the drug. Do not get a live vaccine while taking this drug and avoid people who have recently had a live vaccine. Grapefruit or grapefruit juice can interact with this drug. You should also avoid the following drugs while taking temsirolimus: dexamethasone, rifabutin, rifampin, St.John's wort, sunitinib, antibiotics, antifungal medication, ketoconazole, voriconazole, HIV/AIDS medicine, seizure medication, and phenobarbital. You should not use this medication if you are allergic to any of the ingredients. Tell your doctor if you have high cholesterol or triglycerides, a head injury, brain tumor, or stroke, or if you have diabetes.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.