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How does ergotamine and caffeine treat migraine headaches?

Some scientists believe that ergotamine and caffeine relieve the pain of migraine headaches through their effect on blood vessels in the brain. Although the precise cause of these painful headaches remains mysterious, it's known that ergotamine and caffeine prevent blood vessels from expanding, which may avert the pain. However, some scientists believe that the source of migraine pain may lie elsewhere in the brain.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.