What are the side effects of ambrisentan?

While taking ambrisentan, you may experience constipation, stomach upset or sinus irritation. You may develop headaches, a sore throat from post-nasal drip or feel flushed or tingly below the surface of your skin. If these side effects persist or get worse, contact your doctor  Also, let your doctor know right away if you experience any of the following side effects, as they may be signs of a medical emergency: signs of an allergic reaction, such as hives or an itchy rash, swelling around the mouth or face or chest tightness and difficulty breathing; signs of liver damage, such as nausea, stomach pain, itching, low fever, loss of appetite, dark urine, clay-colored stools or yellowing of the skin or eyes; bloating; irregular heartbeat; unexplained and sudden weight gain; swelling in your limbs or face; unexplained bruising, bleeding, fatigue or vomiting.

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