What should I know about nisoldipine before taking it?

Nisoldipine may cause drowsiness, lightheadedness, and dizziness, particularly when used with alcohol and certain medications. You should not drive or do other dangerous tasks until you are sure how you will react to the drug. Nisoldipine can interact with some medications including cimetidine, fentanyl, phenytoin, and rifampin, as well as beta-blocker medications, diuretics, and HIV protease inhibitor drugs. It is normal to feel tired for weeks when beginning a blood pressure medication like nisoldipine. The drug contains a yellow dye that could cause an allergic reaction. You should not eat grapefruit or drink grapefruit juice while taking nisoldipine. Avoid a high fat meal around the time you take the medication. Nisoldipine should not be used during pregnancy or while breastfeeding.

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