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What is phentolamine?

Phentolamine is used to treat erectile dysfunction. It causes blood vessels to expand, thereby increasing blood flow. When injected into the penis (intracavernosal) it increases blood flow to the penis, which results in an erection. Phentolamine may also be used to reverse the effects of an anesthetic medicine in certain areas, such as the lips and tongue. It may be used to help quickly restore normal sensation and function in patients who have received local dental anesthesia. Although the drug can be helpful for men who have erectile dysfunction, it can cause permanent loss of the ability to have an erection in men who use it improperly.  

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