What should I know before using Hyzaar?

Before you take Hyzaar (losartan and hydrochlorothiazide), a prescription medication used to treat high blood pressure, you should know why your doctor is prescribing it, what you should expect from it and how to take it. You should also know whether you are allergic to losartan or hydrochlorothiazide, the active ingredients in this drug, or to any other drug.

Certain medical conditions can raise your risk of side effects from Hyzaar, so before you start it, give your doctor a complete medical history. Be sure to mention if you have or have ever had any of the following:
  • kidney disease
  • liver disease
  • lupus 
  • gout
  • asthma
  • decreased urine
Because Hyzaar can interact with some other drugs, you should also tell your doctor about all your other medications (prescription and over-the-counter), as well as any supplements you take. Be sure to let him or her know if you're taking any of the following:
  • nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen and COX-2 inhibitors such as celecoxib
  • lithium
  • diuretics (known as water pills)
  • potassium supplements
  • barbiturates
  • blood pressure medications
  • cimetidine
  • corticosteroids
  • diabetes medications
  • fluconazole
  • rifampin
  • skeletal muscle relaxants
  • cholesterol medications
Finally, you should know that it can be dangerous to take Hyzaar if you're pregnant or breastfeeding. If you're pregnant or plan to become pregnant, or if you're breastfeeding, tell your doctor before you start Hyzaar.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.