A Answers (3)
Methyldopa is a Class B drug for pregnancy and for breastfeeding. It is commonly given during pregnancy for Gestational Hypertension and for Chronic HTN during pregnancy. I have seen it used in many pregnancies and the mother did breastfeed later. It is an inexpensive drug and most patients only take it BiD, some only Q day. The most common doses I have seen are 250 mgs BID or 500 mg BID when the BP is elevated above 140/90. It seems to be tolerated well. Any slight risk is better than the complications which uncontrolled "HTN" lead to. i.e. Damage to the kidneys, decreased blood supply to the uterus (needs to be 500 ml) per minute for optimum utero-placental circulation. Anything which causes a decrease in this needed blood supply leads to the risk of preterm labor, damage to the placenta (infarcts), an IUGR (intrauterine growth retardation)fetus, or a SGA (small for gestational age). Uncontrolled "HTN" causes damage to all of the organ systems in the maternal body, and therefore it is essential that it be controlled during pregnancy to promote a healthy pregnancy and a good outcome - a healthy normal baby.