How do amlodipine and valsartan interact with other medications or foods?

Amlodipine-valsartan should not be combined with other angiotensin II receptor blockers (often called 'sartans') or medications containing potassium. Amlodipine-valsartan may also cause harmful drug interactions when combined with angiotensin-converting enzyme (ACE) inhibitors, such as benazepril and captopril; amiloride; amiloride-HCTZ; triamterene; triamterene-HCTZ; digoxin; and eplerenone. In addition, amlodipine-valsartan may interact negatively with prescription and over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen. Alcohol should be avoided when taking this medication. As a safety precaution, the prescribing doctor needs to know about all of the other medications, vitamins and herbal supplements being taken.

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