What is the difference between Diovan and Diovan HCT?

The main difference between Diovan and Diovan HCT is that Diovan contains one active ingredient (valsartan), and Diovan HCT contains two (valsartan and hydrochlorothiazide).

Both these drugs treat high blood pressure. However, Diovan can be used in children ages 6 and up as well as adults, while Diovan HCT has not been shown to be safe and effective in children. Another difference: Diovan is also prescribed for heart failure and to increase the odds of long-term survival after a heart attack. Diovan HCT is not approved for these additional conditions.

Valsartan, an active ingredient in both drugs, belongs to a class of drugs called angiotensin receptor blockers (ARBs), which lower blood pressure by relaxing and dilating blood vessels to improve blood flow. Diovan HCT also contains hydrochlorothiazide, a diuretic that lowers blood pressure by helping the body excrete excess water and salt (sodium). Doctors often prescribe Diovan HCT to people whose blood pressure was not reduced enough by taking Diovan alone or hydrochlorothiazide alone.
The difference between Diovan and Diovan HCT is the ingredient hydrochlorothiazide. Diovan contains valsartan and Diovan HCT contains valsartan plus hydrochlorothiazide. Hydrochlorothiazide is a diuretic and helps to lower blood pressure by pulling excess fluid out of the body. This action should increase urine output. If your urine output is decreasing and becoming more concentrated, there could be a different underlying cause. It is important to make an appointment with your physician as soon as possible and explain this change in your urine output and how you are feeling.

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