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Does Cardizem LA interact with other medications or food?

Cardizem LA (diltiazem hydrochloride) may interact with several other medications. For example, beta-blockers and digoxin can both cause low heart rates and irregular heart rhythms, and the effects of these drugs can add to similar effects caused by Cardizem LA. Cimetidine can decrease the breakdown of Cardizem LA, leading to an increased amount of Cardizem LA in the body and thus increasing the risk of all side effects. In contrast, rifampin can increase the rate of breakdown of Cardizem LA, thus decreasing the amount of the drug in the body and reducing its effectiveness. Cardizem LA may affect drugs such as buspirone, benzodiazepines (especially midazolam and triazolam), carbamazepime, cyclosporine, lovastatin, simvastatin and quinidine, increasing the amount of these drugs in the body and therefore increasing the risk for side effects. It is important to tell your doctor about all medications and supplements you take before starting on this medication.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.