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Are there any risks in taking Lotrel (amlodipine and benazepril)?

There are some risks in taking Lotrel. Pregnant women taking the drug can cause harm to the developing fetus and nursing mothers can cause harm to their nursing baby. Lotrel can cause severe allergic responses and a condition called intestinal angioedema, which is characterized by intense stomach pain. After the first dose, you may become dizzy or feel faint, which can be especially dangerous if you are driving or operating machinery. Lotrel may increase the risk of becoming dehydrated, which could result in dangerously low blood pressure. If you experience symptoms of chills, throat pain or fever, you may have an infection, which could result from decreased white blood cell counts, if your kidneys are not functioning properly. Liver problems and hyperkalemia (increased potassium in the blood) can result when you are taking Lotrel. Surgery may carry additional risk when taking this medication, and some individuals experience sore or bleeding gums soon after beginning treatment. African-Americans might have decreased sensitivity to Lotrel's effects of lowering the blood pressure, as well as an increased risk of serious allergic reaction related to swelling. Because of the risks associated with Lotrel, it is extremely important to have regular medical check-ups to ensure that the medication is working successfully.

 

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